General Information of EM (ID: EM00600)
  Official Symbol
H2BC21
  Official Full Name
H2B clustered histone 21
  Synonym
H2B;H2B.1;H2B/q;H2BE;H2BFQ;HIST2H2BE
  Molecule Type
Protein coding
  Position On Chromosome
chr1(Start:149884459 - End:149886652)
  Strand
-
  ENSG ID
ENSG00000184678 
    Disease Relevance (Click to Show/Hide)
         2A00: Primary neoplasms of brain Glioma [Primary neoplasms of brain]
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         2B70: Malignant neoplasms of oesophagus Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus]
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         2B70: Malignant neoplasms of oesophagus Esophageal adenocarcinoma (EAC) [Malignant neoplasms of oesophagus]
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         2C60: Carcinoma of breast Breast cancer [Carcinoma of breast]
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         8A20: Alzheimer disease Alzheimer's disease [Alzheimer disease]
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         9A01: Infectious disorders of eyelid Human eye and its diseases [Infectious disorders of eyelid]
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         FA20: Rheumatoid arthritis Rheumatoid arthritis [Rheumatoid arthritis]
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         GA10: Endometriosis Endometriosis [Endometriosis]
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         JA24: Pre-eclampsia Preeclampsia (PE) [Pre-eclampsia]
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         XB8M: Congenital Melanoma [Congenital]
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         XH3DV3: Adenoma Adenoma [Adenoma]
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         XH6PH6: Astrocytoma Astrocytoma [Astrocytoma]
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         XH7F82: Glioblastoma Glioblastoma [Glioblastoma]
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         XH8SH6: CNS embryonal tumour Primitive neuroectodermal tumors [CNS embryonal tumour]
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         XH9HQ1: Gastrointestinal stromal tumour Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour]
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Protein(s) with this epigenetic modification
  Protein Name: Rv2966c
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Rv2966c could hypermethylate the non-CpG dinucleotides at the host HIST2H2BE (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.

References
1 Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006.

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