Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM00600) | |||||||
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| Official Symbol |
H2BC21
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| Official Full Name |
H2B clustered histone 21
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| Synonym |
H2B;H2B.1;H2B/q;H2BE;H2BFQ;HIST2H2BE
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr1(Start:149884459 - End:149886652)
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| Strand |
-
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| ENSG ID | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
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| 2B70: Malignant neoplasms of oesophagus | Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus] | ||||||
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| 2B70: Malignant neoplasms of oesophagus | Esophageal adenocarcinoma (EAC) [Malignant neoplasms of oesophagus] | ||||||
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| 2C60: Carcinoma of breast | Breast cancer [Carcinoma of breast] | ||||||
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| 8A20: Alzheimer disease | Alzheimer's disease [Alzheimer disease] | ||||||
| Detailed Information |
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| 9A01: Infectious disorders of eyelid | Human eye and its diseases [Infectious disorders of eyelid] | ||||||
| Detailed Information |
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| FA20: Rheumatoid arthritis | Rheumatoid arthritis [Rheumatoid arthritis] | ||||||
| Detailed Information |
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| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
| Detailed Information |
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| JA24: Pre-eclampsia | Preeclampsia (PE) [Pre-eclampsia] | ||||||
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| XB8M: Congenital | Melanoma [Congenital] | ||||||
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| XH3DV3: Adenoma | Adenoma [Adenoma] | ||||||
| Detailed Information |
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| XH6PH6: Astrocytoma | Astrocytoma [Astrocytoma] | ||||||
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| XH7F82: Glioblastoma | Glioblastoma [Glioblastoma] | ||||||
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| XH8SH6: CNS embryonal tumour | Primitive neuroectodermal tumors [CNS embryonal tumour] | ||||||
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| XH9HQ1: Gastrointestinal stromal tumour | Gastrointestinal stromal tumors (GIST) [Gastrointestinal stromal tumour] | ||||||
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host HIST2H2BE (intergenic) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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