Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM00123) | |||||||
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| Official Symbol |
PRAMEF5
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| Official Full Name |
PRAME family member 5
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr1(Start:13254212 - End:13263314)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Disease Relevance (Click to Show/Hide) | |||||||
| 2A00: Primary neoplasms of brain | Glioma [Primary neoplasms of brain] | ||||||
| Detailed Information |
Disease Link
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| 2B6B: Malignant neoplasms of nasopharynx | Nasopharyngeal carcinoma (NPC) [Malignant neoplasms of nasopharynx] | ||||||
| Detailed Information |
Disease Link
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| 2B70: Malignant neoplasms of oesophagus | Barrett's esophagus and esophageal adenocarcinoma [Malignant neoplasms of oesophagus] | ||||||
| Detailed Information |
Disease Link
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| GA10: Endometriosis | Endometriosis [Endometriosis] | ||||||
| Detailed Information |
Disease Link
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| JA24: Pre-eclampsia | Preeclampsia (PE) [Pre-eclampsia] | ||||||
| Detailed Information |
Disease Link
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| LA02: Spina bifida | Neural tube defects (NTDs) [Spina bifida] | ||||||
| Detailed Information |
Disease Link
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| XH4W48: Hepatocellular carcinoma | Hepatocellular carcinoma (HCC) [Hepatocellular carcinoma] | ||||||
| Detailed Information |
Disease Link
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| XH85Z0: Neuroblastoma | Neuroblastoma [Neuroblastoma] | ||||||
| Detailed Information |
Disease Link
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| XH8AA5: Acute myeloid leukaemia | Acute myeloid leukemia (AML) [Acute myeloid leukaemia] | ||||||
| Detailed Information |
Disease Link
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| XH8P29: Medulloblastoma | Medulloblastoma [Medulloblastoma] | ||||||
| Detailed Information |
Disease Link
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| XH8SH6: CNS embryonal tumour | Primitive neuroectodermal tumors [CNS embryonal tumour] | ||||||
| Detailed Information |
Disease Link
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| Protein(s) with this epigenetic modification | |||||||
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| Protein Name: Rv2966c | |||||||
| Detailed Information |
Pro Info
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[1] | |||||
| Description |
Rv2966c could hypermethylate the non-CpG dinucleotides at the host PRAMEF5 (geneBody) genetic loci during Mycobacterium tuberculosis H37Rv infection.
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| References | |||||
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| 1 | Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. Sci Rep. 2016 Apr 26;6:25006. doi: 10.1038/srep25006. | ||||
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