Details of Epigenetic Molecule(EM)
| General Information of EM (ID: EM00070) | |||||||
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| Official Symbol |
CIITA
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| Official Full Name |
class II, major histocompatibility complex, transactivator
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| Synonym |
C2TA;MHC2TA;NLRA
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| Molecule Type |
Protein coding
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| Position On Chromosome |
chr16(Start:10866222 - End:10943021)
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| Strand |
+
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| Uniprot Entry | |||||||
| ENSG ID | |||||||
| Dnmivd Disease | |||||||
| Protein(s) with this epigenetic modification | |||||||
|---|---|---|---|---|---|---|---|
| Protein Name: LpqH | |||||||
| Detailed Information |
Pro Info
 click to show the detail information of this protein
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[1] | |||||
| Description |
LpqH could be block the IFN-gama-induced transcription of CIITA through inhibition of SWI/SNF binding and histone deacetylation at the CIITA promoter.
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| References | |||||
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| 1 | Histone modifications and chromatin remodeling during bacterial infections. Cell Host Microbe. 2008 Aug 14;4(2):100-9. doi: 10.1016/j.chom.2008.07.009. | ||||
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