Details of Epigenetic Molecule(EM)

General Information of EM (ID: EM00066)
  Official Symbol
CDH1
  Official Full Name
cadherin 1
  Synonym
CD324;UVO;uvomorulin
  Molecule Type
Protein coding
  Position On Chromosome
chr16(Start:68737292 - End:68835537)
  Strand
+
  Uniprot Entry
P12830 
  ENSG ID
ENSG00000039068 
  Dnmivd Disease
COAD 
Protein(s) with this epigenetic modification
  Protein Name: Transposase
     Detailed Information Pro Info click to show the detail information of this protein [1]
     Description
Transposase could be induce the DNA methylation in the promoters of E-cadherin gene.
  Protein Name: Transposase
     Detailed Information Pro Info click to show the detail information of this protein [1], [2]
     Description
Transposase could be induce the DNA methylation in the promoters of E-cadherin gene.
  Protein Name: LMP-1
     Detailed Information Pro Info click to show the detail information of this protein [3]
     Description
The latent membrane protein 1 (LMP-1) has been shown to activate DNMTs to hypermethylate and gene silencing of the E-cadherin gene.

References
1 Nuclear translocation of Acinetobacter baumannii transposase induces DNA methylation of CpG regions in the promoters of E-cadherin gene PLoS One. 2012;7(6):e38974. doi: 10.1371/journal.pone.0038974. Epub 2012 Jun 7.
2 Microbial co-habitation and lateral gene transfer: what transposases can tell us Genome Biol. 2009;10(4):R45. doi: 10.1186/gb-2009-10-4-r45. Epub 2009 Apr 24.
3 Cumulative Epigenetic Abnormalities in Host Genes with Viral and Microbial Infection during Initiation and Progression of Malignant Lymphoma/Leukemia. Cancers (Basel). 2011 Feb 4;3(1):568-81. doi: 10.3390/cancers3010568.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.